Ginseng Siberian

Ginseng Siberian- Acanthopanax Senticosus

Scientific name – Siberian Ginseng, Eleutherococcus senticosus


Siberian Ginseng belongs to Araliaceae family.

Other names of this plant

Acanthopanax Obovatus, Acanthopanax Obovatus Hoo, Acanthopanax senticosus, Buisson du Diable, Ci Wu Jia, Ciwujia, Ciwujia Root, Ciwujia Root Extract, Devil’s Bush, Devil’s Shrub, Éleuthéro, Eleuthero Extract, Eleuthero Ginseng, Eleuthero Root, Eleutherococci Radix, Eleutherococcus senticosus, Éleuthérocoque, Ginseng de Sibérie, Ginseng des Russes, Ginseng Root, Ginseng Siberiano, Ginseng Sibérien, Hedera senticosa, North Wu Jia Pi, Phytoestrogen, Plante Secrète des Russes, Poivre Sauvage, Prickly Eleutherococcus, Racine d’Eleuthérocoque, Racine de Ginseng, Racine Russe, Russian Root, Shigoka, Siberian Eleuthero, Siberian Ginseng, Thorny Bearer of Free Berries, Touch-Me-Not, Untouchable, Ussuri, Ussurian Thorny Pepperbrush, Wild Pepper, Wu Jia Pi, Wu-jia, Ci wu jia, Devil’s Root, Eleuthero, Eleutherococcus Senticosus, Shigoka, Touch-Me-Not, Wuchaseng,

Herb Overview

Siberian Ginseng is an herb that belongs to the adaptogens. It is a small, woody shrub in the family  of Araliaceae. It has been noted that Eleutherocuccus can reach heights of as much as 10 feet tall. herb has anywhere from three to seven leaves and each leaf appears somewhat “toothed.” The plant also has tiny thorns.  Siberian Ginseng is native to Northeastern Asia-  China, Japan, Korea and Russia. In fol medicine it was mainly used  to balance the bodily balance, stimulate the  appetite. It was well known for its capability to suppress the  fatigue, to to improve memory function and increase the longevity. It is believed that ginseng may  to improve endurance, increase bodily vigor and stamina, may also be helpful with certain sexual dysfunctions. It was reported that Siberian Ginseng may help in fighting  with the process of aging, improving the function of the adrenal glands and reducing the symptoms associated with anxiety and stress. It is believed, that Siberian Ginseng may improve magalocyte counts and balance  immune system, however there is a lack of scientific data to promote this claim. Siberian Ginseng is also noted for its mood elevating properties. All Acanthopanax Senticosus products are derived from eleutherosides and polysaccharides  that are found in the plant’s root.

Parts of the plant used

All Acanthopanax Senticosus products are derived from eleutherosides and polysaccharides found in the plant’s root. Leaves and bark of the plant are not used.

Medicinal uses

Siberian ginseng is traditionally used for low blood pressure, hardening of the arteries (atherosclerosis), and rheumatic heart disease.It is also used to boost the immune system and prevent colds. It may also  increase the appetite.

It is also sometimes used for Alzheimer’s disease, insomnia, attention deficit-hyperactivity disorder (ADHD), chronic fatigue syndrome, colds, chronic bronchitis. Some people use Siberian ginseng to improve athletic performance, general endurance and the ability to do the  work. In folk medicine it was used in diabetes, fibromyalgia, rheumatoid arthritis, tuberculosis. It is also used for treating the side effects of cancer chemotherapy. Siberian ginseng can also be added to skin care products.

Uses of Acantopax Senticosus

Endurance and physical performance

It is blieved that  Siberian Ginseng can balance whatever is out of balance in the body. However the real scientific data shows that it may be helpful in coping with certain environmental stressors.

Boosting immune system

Studies have shown that individuals taking Acanthopanax Senticosus show extensive augmentations in terms of immune system functioning. Individuals taking Acanthopanax Senticosus on a regular basis have increased bodily strength, can better cope with environmental stressors and have fewer cold or flu-like symptoms.

Reproductive Benefits

Numerous animal studies indicate that Acanthopanax Senticosus may improve  fertility.

Memory Benefits

It is believed, that the extracts of this plant may help  to enhance the state of one’s alertness . There had been several studies, that suggest that it may also be helpful in one’s ability to concentrate and improve the moemory.

Overall Health Benefits

Laboratory studies showed, that extract of this herb that can inhibit the reproduction of certain viruses, especially the flu virus. It also affects herpes simplex type 2 virus and does reduce the frequency of eruptions.  Taking a specific Siberian ginseng extract, (eleutheroside 0.3% (Elagen)), seems to reduce the number, severity, and duration of herpes simplex type 2 infections. However the extract is not able to cure from the infection.

Quality of life

Some research shows that Siberian ginseng  may be helpful in dealing with aging and mental decline. It significantly improves sociability and sense of well-being in people over 65 years of age after 4 weeks of treatment. However, the effects seem to be short- termed and   seem to disappear after 8 weeks.

Bipolar disorder

Taking Siberian ginseng with lithium by mouth for 6 weeks appears to induce a similar response rate and remission rate as taking lithium and fluoxetine in people with bipolar disorder.

Common cold

Extracts of Siberian Ginseng  used in in combination with a herb  andrographis (Kan Jang, Swedish Herbal Institute) by mouth improved symptoms of the common cold when it was started within 72 hours of symptom onset. However, it generally takes at least 4-5 days of treatment for the maximum benefit of the herb.

More evidence is needed for usage of  Eleutherococcus  in these  medical conditions

Improving athletic performance.
Chronic fatigue syndrome.
Mental performance.
Familial Mediterranean fever.
Heart diseases
Flu and common cold
Quality of life
Kidney problems.
Alzheimer’s disease.
Attention deficit-hyperactivity disorder (ADHD)
High cholesterol
Chemotherapy side effects.
Low oxygen levels
Motion sickness

Types Available

Siberian Ginseng can be purchased as an extract, as capsules, tablets. Sometimes  the dried root can be used as a tea. Additionally, tinctures can be made out of Acanthopanax Senticosus .

Side effects

Siberian ginseng is LIKELY SAFE for most adults when it is taken by mouth and used for the short-term.

Side effects are rare. They include drowsiness, changes in heart rhythm, sadness, anxiety, muscle spasms. When high doses are used- it may increase the blood pressure. In high doses, increased blood pressure might occur.

Acanthopanax Senticosus can also cause irritability, restlessness, insomnia and nervousness .

It should be taken in the morning, as it may cause sleep disorders.

Siberian ginseng is POSSIBLY SAFE for most adults when taken by mouth, long-term.

Special Precautions and  Warnings


Siberian ginseng is not used for little children until age 12. Siberian ginseng is POSSIBLY SAFE in teenagers (ages 12-17 years) when it is taken by mouth for up to 6 weeks. No data about the safety for long term use in this age group.

Pregnancy and breast-feeding

There is not enough reliable information about the safety of taking Siberian ginseng if you are pregnant or breast-feeding. Stay on the safe side and avoid  the use of this herb.

Bleeding disorders

In theory, Siberian ginseng might increase the risk of bleeding and bruising in people with bleeding disorders, it is better not to use this supplement in this case.

Heart conditions

Siberian ginseng can cause  irregular heartbeat, and high blood pressure. People who have heart disorders  should use Siberian ginseng only under a healthcare provider’s supervision.


Siberian ginseng might iinteract with blood sugar. You should monitor your blood sugar carefully if you take Siberian ginseng and have diabetes.

Hormone-sensitive conditions such as breast cancer, uterine cancer, ovarian cancer, endometriosis, or uterine fibroids

Siberian ginseng might act like  hormone estrogen. If you have any condition that might be made worse by exposure to estrogens,  you should not  use Siberian ginseng.

High blood pressure

Siberian ginseng should not be used by people who tend to have higher blood pressure. Siberian ginseng might make high blood pressure worse.

Mental conditions such as mania or schizophrenia

Siberian ginseng might make these conditions worse. Do not use this supplement.


It is recommended that individuals contact a professional before taking the herb.

People that have sleep apnea, narcolepsy, or other sleep problems should avoid using Acanthopanax Senticosus .

Interactions with drugs


Alcohol causes sleepiness and drowsiness. Eleutherococcus might also cause sleepiness and drowsiness. Avoid taking Siberian ginseng along with alcohol.

Digoxin (Lanoxin) 

Digoxin (Lanoxin) may interact with Siberian Ginseng. Avoid taking together.

Lithium interacts with Siberian ginseng . Avoid taking together.

Medications changed by the liver (Cytochrome P450 1A2 (CYP1A2) substrates) 

Clozapine (Clozaril), cyclobenzaprine (Flexeril), fluvoxamine (Luvox), haloperidol (Haldol), imipramine (Tofranil), mexiletine (Mexitil), olanzapine (Zyprexa), pentazocine (Talwin), propranolol (Inderal), tacrine (Cognex), theophylline, zileuton (Zyflo), zolmitriptan (Zomig), and others may interact with Eleutherococcus. Avoid taking them together.

Medications changed by the liver (Cytochrome P450 2C9 (CYP2C9) substrates) 

Amitriptyline (Elavil), diazepam (Valium), zileuton (Zyflo), celecoxib (Celebrex), diclofenac (Voltaren), fluvastatin (Lescol), glipizide (Glucotrol), ibuprofen (Advil, Motrin), irbesartan (Avapro), losartan (Cozaar), phenytoin (Dilantin), piroxicam (Feldene), tamoxifen (Nolvadex), tolbutamide (Tolinase), torsemide (Demadex), warfarin (Coumadin), and others may interact with Eleutherococcus- avoid taking them together.

Medications for diabetes (Antidiabetes drugs) 

Siberian ginseng might affect blood sugar, either lowering or increasing blood sugar levels.  Taking Siberian ginseng along with diabetes medications might interfer with the controls of your blood sugar.

Some medications used for diabetes include glimepiride (Amaryl), glyburide (DiaBeta, Glynase PresTab, Micronase), insulin, pioglitazone (Actos), rosiglitazone (Avandia), chlorpropamide (Diabinese), glipizide (Glucotrol), tolbutamide (Orinase), and others.

Blood clotting medications (Anticoagulant / Antiplatelet drugs) 

Siberian ginseng might slow blood clotting, avoid taking it with those medications that affect blood clotting. Such as  aspirin, clopidogrel (Plavix), diclofenac (Voltaren, Cataflam, others), ibuprofen (Advil, Motrin, others), naproxen (Anaprox, Naprosyn, others), dalteparin (Fragmin), enoxaparin (Lovenox), heparin, warfarin (Coumadin), and others.

Sedative medications (CNS depressants) 

Siberian ginseng might cause sleepiness and drowsiness. Avoid taking it with such medications as clonazepam (Klonopin), lorazepam (Ativan), phenobarbital (Donnatal), zolpidem (Ambien), and others.